Vesi-SEC micro
Size Exclusion Chromatography spin-columns
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For the fast and effective removal of excess reagent pre-extracellular vesicles & bio-nano particles analytics.
Increase your assay sensitivity by removing excess fluorescent dye or antibody post-incubation in an instant, little to no loss of material.
Because analysis at the nanoscale is much more sensitive to residues and impurities, removing excess reagent before analysis is key to the generation of reliable data. With Vesi-SEC micro spin-columns, this clean-up step is done in one minute, without significant loss of material and dilution.
Incubate → Clean-up → Progress
You no longer have to choose between yield and sensitivity
Centrifugal SEC made possible by Core-Sep stationary phase.
Vesiculab is using a proprietary gel, Core-Sep, which offers physical properties compatible with the use of centrifugal force. With beads ranging 40µm-70µm and a pore size range of 30nm to 40nm, Core-Sep offers the ideal performance for removing small molecule and biologics contaminant from nanoparticles samples, such as extracellular vesicles / exosomes, OMVs, lentiviruses, adenoviruses, liposomes, LNPs and more.
Vesi-SEC micro spin-columns can be used for sample clean-up before analysis using the following techniques:
- Flow Cytometry (FCM)
- Fluorescence Nanoparticle Tracking Analysis (f-NTA)
- Fluorescence microfluidics resistive pulse sensing (F-MRPS)
- Nano-Flow Cytometry (nFCM)
- Confocal microscopy
- Single-molecule localization microscopy (SMLM)
- Single-particle interferometric reflectance imaging sensor (SP-IRIS)
Simple Operation
- Step 1. Remove the storage buffer
- Step 2. Wash with clean buffer
- Step 3. Load sample and elute
Easy To Scale-Up
Prepare up to 104 samples at the time by using larger model centrifuges. Vesi-SEC micro spin-columns are best operated in swing-bucket centrifuges, rather than fixed-rotor types, as they keep sample elution on a straight, horizontal path.
Vesi-SEC micro Technical Information
| Format | Spin columns containing 500µL Core-Sep gel |
| Quantity | 24 spin columns per box |
| Storage conditions | Up to 3 years at 4-6°C |
| Notes | For optimal performance, use swing-bucket rotor centrifuge |
